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Drospirenone-Ethinyl Estradiol Disp Pack — prescription drug image

Drospirenone-Ethinyl Estradiol

Drospirenone-Ethinyl Estradiol 28 Tablets

Women's Health Care
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What is Drospirenone-Ethinyl Estradiol?

Ocella is an oral contraceptive used in the prevention of pregnancy. The generic version of Ocella is Drospirenone-Ethinyl Estradiol. On average, Ocella is priced at about $72 for a supply of 28, 3-0.03 mg tablets. You can significantly lower the price of Ocella by using our free Singlecare coupon card at a local participating pharmacy.

Prescription savings · · · ·

What is Drospirenone-Ethinyl Estradiol ?

Ocella is an oral contraceptive used in the prevention of pregnancy. The generic version of Ocella is Drospirenone-Ethinyl Estradiol. On average, Ocella is priced at about $72 for a supply of 28, 3-0.03 mg tablets. You can significantly lower the price of Ocella by using our free Singlecare coupon card at a local participating pharmacy.
  • Nausea
  • Headache
  • Breast tenderness
  • Breakthrough bleeding
  • Weight gain
  • Increased risk of blood clots
  • Not recommended for smokers over the age of 35
  • Not for use during pregnancy
  • May increase blood pressure
  • Should be used with caution in individuals with a history of heart disease or stroke
Is drospirenone and ethinyl estradiol the same as Yaz or Yasmin?
Yes. Drospirenone / ethinyl estradiol is the generic version of brand-name pills like Yaz and Yasmin (it is also sold as Ocella and under several other names). The generic contains the same active hormones as the brand, so it works the same way and is usually less expensive.
Does drospirenone-ethinyl estradiol help with acne?
Certain products, specifically the Yaz formulation, are FDA-approved to treat moderate acne in women at least 14 years old who also want to use the pill for birth control. Not every drospirenone / ethinyl estradiol product is approved for acne, so ask your provider whether it is appropriate for you.
Can drospirenone-ethinyl estradiol cause weight gain?
Weight changes and fluid retention are commonly asked about with birth control pills, but responses vary from person to person. If you notice changes that concern you after starting the pill, talk with your provider — do not stop taking it on your own.
What are the most common side effects of drospirenone and ethinyl estradiol?
Common side effects can include nausea, breast tenderness, headache, spotting or bleeding between periods, and mood changes. Seek medical care right away for signs of a blood clot or other serious problem, such as severe leg pain or swelling, chest pain, sudden shortness of breath, a severe headache, or vision changes.
Who should not take drospirenone-ethinyl estradiol?
It should not be used by women over 35 who smoke, or by people with a history of blood clots, certain cancers, liver disease, uncontrolled high blood pressure, or migraine with aura, and it is not used during pregnancy. Extra caution and potassium monitoring may be needed if you have kidney, liver, or adrenal problems or take other potassium-raising medicines. Your provider can review your health history to see if it is safe for you.
How much does Drospirenone-Ethinyl Estradiol cost without insurance?
The price of Drospirenone-Ethinyl Estradiol without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Drospirenone-Ethinyl Estradiol?
Common side effects of Drospirenone-Ethinyl Estradiol may include: Nausea, Headache, Breast tenderness, Breakthrough bleeding, Weight gain. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Drospirenone-Ethinyl Estradiol?
Generic versions may be available for Drospirenone-Ethinyl Estradiol. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Drospirenone-Ethinyl Estradiol on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Drospirenone-Ethinyl Estradiol?
The cheapest pharmacy for Drospirenone-Ethinyl Estradiol depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Drospirenone-Ethinyl Estradiol near you.

Drospirenone-Ethinyl Estradiol Coupons & Prices

Drospirenone-Ethinyl Estradiol 28 Tablets

Women's Health Care
Licensed US providers · Online visit in minutes
Drospirenone-Ethinyl Estradiol Disp Pack — prescription drug image
Prescription
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Looking for a drospirenone-ethinyl-estradiol coupon? This combination birth control pill is the generic version of brand-name products like Yaz and Yasmin, and because it is available as a low-cost generic the cash price is usually modest — but it can still vary widely from one pharmacy to the next. That is why comparing matters. Rx.com checks live discount prices at more than 60,000 pharmacies so you can find today's lowest cost near you. Enter your ZIP above to see the current price at pharmacies in your area and use a free Rx.com coupon at the counter.

What is drospirenone / ethinyl estradiol and how does it work?

Drospirenone / ethinyl estradiol is a combination oral contraceptive (birth control pill) that contains two hormones: an estrogen (ethinyl estradiol) and a progestin (drospirenone). Drospirenone is a progestin derived from spironolactone, which gives it mild antimineralocorticoid and antiandrogenic activity. Taken as directed, the pill prevents pregnancy by stopping ovulation and changing the uterine lining and cervical mucus. It is sold under many brand names, including Yaz, Yasmin, Ocella, Gianvi, Loryna, Syeda, Zarah, Vestura, Nikki, and Jasmiel.

The pill is FDA-approved to prevent pregnancy. Certain products (the Yaz formulation) are also approved to treat moderate acne in women at least 14 years old who want oral contraception, and to treat premenstrual dysphoric disorder (PMDD) in women who choose the pill for birth control. It does not protect against HIV or other sexually transmitted infections. Your provider can help you decide whether this pill is a good fit for you.

Cost and savings without insurance

Because drospirenone / ethinyl estradiol is available as a generic, it is generally one of the more affordable combination birth control options, even without insurance. Still, cash prices are not the same everywhere — the same prescription can cost noticeably more at one pharmacy than at another down the street. Comparing before you fill is the single easiest way to avoid overpaying.

Rx.com compares live discount prices across more than 60,000 U.S. pharmacies and gives you a free coupon to use at the pharmacy counter. There is no membership required. Enter your ZIP above to see today's price near you. Prices change often and are shown live on this page, so always check the current amount before you go.

Brand equivalents and similar birth control options

Drospirenone / ethinyl estradiol is the generic of the brand-name pills Yaz and Yasmin, and it is also sold as Ocella. These contain the same active ingredients as the generic, so many people choose the generic to save money. If your provider recommends a different type of combination pill, other common options use a different progestin, such as norethindrone / ethinyl estradiol, norgestimate / ethinyl estradiol, or levonorgestrel / ethinyl estradiol.

One difference worth discussing with your provider: drospirenone-containing pills may carry a somewhat higher risk of blood clots (venous thromboembolism) than pills that use levonorgestrel. The right choice depends on your health history and preferences, so this is a good conversation to have before switching.

Safety, warnings, and side effects

This is a summary, not medical advice — talk with your doctor or pharmacist about your personal risks. Drospirenone / ethinyl estradiol carries a boxed warning that cigarette smoking increases the risk of serious cardiovascular events; this risk rises with age and amount smoked, so the pill should not be used by women over 35 who smoke. Combination pills also increase the risk of blood clots, stroke, and heart attack. Because drospirenone can raise potassium levels (hyperkalemia), your provider may monitor potassium if you have kidney, liver, or adrenal problems or take other potassium-raising medicines such as ACE inhibitors, ARBs, potassium-sparing diuretics, NSAIDs, or aldosterone antagonists.

The pill is contraindicated in people with a history of blood clots, certain cancers, liver disease, uncontrolled high blood pressure, migraine with aura, and in pregnancy. Common side effects can include nausea, breast tenderness, headache, spotting between periods, and mood changes. Call your provider about severe leg pain or swelling, chest pain, sudden shortness of breath, severe headache, or vision changes. This information does not replace guidance from your healthcare provider.

Sources & accuracy

This Drospirenone-Ethinyl Estradiol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Drospirenone-Ethinyl Estradiol on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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