Drospirenone-Ethinyl Estradiol
Drospirenone-Ethinyl Estradiol 28 Tablets
What is Drospirenone-Ethinyl Estradiol?
Ocella is an oral contraceptive used in the prevention of pregnancy. The generic version of Ocella is Drospirenone-Ethinyl Estradiol. On average, Ocella is priced at about $72 for a supply of 28, 3-0.03 mg tablets. You can significantly lower the price of Ocella by using our free Singlecare coupon card at a local participating pharmacy.Side Effects
- Nausea
- Headache
- Breast tenderness
Warnings
- Increased risk of blood clots
- Not recommended for smokers over the age of 35
- Not for use during pregnancy
- May increase blood pressure
- Should be used with caution in individuals with a history of heart disease or stroke
Prescription savings · · · ·
What is Drospirenone-Ethinyl Estradiol ?
Ocella is an oral contraceptive used in the prevention of pregnancy. The generic version of Ocella is Drospirenone-Ethinyl Estradiol. On average, Ocella is priced at about $72 for a supply of 28, 3-0.03 mg tablets. You can significantly lower the price of Ocella by using our free Singlecare coupon card at a local participating pharmacy.- Nausea
- Headache
- Breast tenderness
- Breakthrough bleeding
- Weight gain
- Increased risk of blood clots
- Not recommended for smokers over the age of 35
- Not for use during pregnancy
- May increase blood pressure
- Should be used with caution in individuals with a history of heart disease or stroke
Drospirenone-Ethinyl Estradiol Coupons & Prices
Drospirenone-Ethinyl Estradiol 28 Tablets
4 ED medications in one dose
Sildenafil, tadalafil, vardenafil & apomorphine · Works in ~15 min · Lasts up to 36 hours
Looking for a drospirenone-ethinyl-estradiol coupon? This combination birth control pill is the generic version of brand-name products like Yaz and Yasmin, and because it is available as a low-cost generic the cash price is usually modest — but it can still vary widely from one pharmacy to the next. That is why comparing matters. Rx.com checks live discount prices at more than 60,000 pharmacies so you can find today's lowest cost near you. Enter your ZIP above to see the current price at pharmacies in your area and use a free Rx.com coupon at the counter.
What is drospirenone / ethinyl estradiol and how does it work?
Drospirenone / ethinyl estradiol is a combination oral contraceptive (birth control pill) that contains two hormones: an estrogen (ethinyl estradiol) and a progestin (drospirenone). Drospirenone is a progestin derived from spironolactone, which gives it mild antimineralocorticoid and antiandrogenic activity. Taken as directed, the pill prevents pregnancy by stopping ovulation and changing the uterine lining and cervical mucus. It is sold under many brand names, including Yaz, Yasmin, Ocella, Gianvi, Loryna, Syeda, Zarah, Vestura, Nikki, and Jasmiel.
The pill is FDA-approved to prevent pregnancy. Certain products (the Yaz formulation) are also approved to treat moderate acne in women at least 14 years old who want oral contraception, and to treat premenstrual dysphoric disorder (PMDD) in women who choose the pill for birth control. It does not protect against HIV or other sexually transmitted infections. Your provider can help you decide whether this pill is a good fit for you.
Cost and savings without insurance
Because drospirenone / ethinyl estradiol is available as a generic, it is generally one of the more affordable combination birth control options, even without insurance. Still, cash prices are not the same everywhere — the same prescription can cost noticeably more at one pharmacy than at another down the street. Comparing before you fill is the single easiest way to avoid overpaying.
Rx.com compares live discount prices across more than 60,000 U.S. pharmacies and gives you a free coupon to use at the pharmacy counter. There is no membership required. Enter your ZIP above to see today's price near you. Prices change often and are shown live on this page, so always check the current amount before you go.
Brand equivalents and similar birth control options
Drospirenone / ethinyl estradiol is the generic of the brand-name pills Yaz and Yasmin, and it is also sold as Ocella. These contain the same active ingredients as the generic, so many people choose the generic to save money. If your provider recommends a different type of combination pill, other common options use a different progestin, such as norethindrone / ethinyl estradiol, norgestimate / ethinyl estradiol, or levonorgestrel / ethinyl estradiol.
One difference worth discussing with your provider: drospirenone-containing pills may carry a somewhat higher risk of blood clots (venous thromboembolism) than pills that use levonorgestrel. The right choice depends on your health history and preferences, so this is a good conversation to have before switching.
Safety, warnings, and side effects
This is a summary, not medical advice — talk with your doctor or pharmacist about your personal risks. Drospirenone / ethinyl estradiol carries a boxed warning that cigarette smoking increases the risk of serious cardiovascular events; this risk rises with age and amount smoked, so the pill should not be used by women over 35 who smoke. Combination pills also increase the risk of blood clots, stroke, and heart attack. Because drospirenone can raise potassium levels (hyperkalemia), your provider may monitor potassium if you have kidney, liver, or adrenal problems or take other potassium-raising medicines such as ACE inhibitors, ARBs, potassium-sparing diuretics, NSAIDs, or aldosterone antagonists.
The pill is contraindicated in people with a history of blood clots, certain cancers, liver disease, uncontrolled high blood pressure, migraine with aura, and in pregnancy. Common side effects can include nausea, breast tenderness, headache, spotting between periods, and mood changes. Call your provider about severe leg pain or swelling, chest pain, sudden shortness of breath, severe headache, or vision changes. This information does not replace guidance from your healthcare provider.
This Drospirenone-Ethinyl Estradiol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Drospirenone-Ethinyl Estradiol on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Browse more medications: starting with D · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.