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Olmesartan Medoxomil-Hctz Tablet — prescription drug image

Olmesartan Medoxomil-Hctz

Olmesartan Medoxomil-HCTZ 40-25MG

Prescriptions & Refills
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What is Olmesartan Medoxomil-Hctz?

Benicar HCT is used to help lower high blood pressure. Hydrochlorothiazide/Olmesartan is the generic version of Benicar HCT. The average Benicar HCT price is about $368 for a supply of 30, 40 mg-25 mg tablets. You can use our Single Care savings offer to get an average Benicar HCT discount of up to 80% off of the retail price at participating pharmacies near you.

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What is Olmesartan Medoxomil-Hctz ?

Benicar HCT is used to help lower high blood pressure. Hydrochlorothiazide/Olmesartan is the generic version of Benicar HCT. The average Benicar HCT price is about $368 for a supply of 30, 40 mg-25 mg tablets. You can use our Single Care savings offer to get an average Benicar HCT discount of up to 80% off of the retail price at participating pharmacies near you.
  • Change in how much or how often you urinate, bloody or cloudy urine
  • Confusion, weakness, muscle twitching
  • Fast, slow, or uneven heartbeat, chest pain
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dry mouth, increased thirst, muscle cramps, nausea, vomiting
  • Lightheadedness, dizziness, or fainting
  • Blistering, peeling, or red skin rash
  • Eye pain, vision changes, seeing halos around lights
  • Severe diarrhea with weight loss (could occur months to years after you start taking this medicine)
  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have kidney problems or trouble urinating, liver disease, heart failure, diabetes, glaucoma, gout, high cholesterol, lupus, or a history of asthma or allergies, including a sulfa or penicillin allergy.
  • This medicine may cause the following problems:Vision changesKidney problemsLow or high levels of minerals in your blood (including potassium and sodium)
  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel dizzy or lightheaded.
  • Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting while you are using this medicine.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Lightheadedness, dizziness, or fainting
  • Severe diarrhea with weight loss (could occur months to years after you start taking this medicine)
What is olmesartan-hydrochlorothiazide (Benicar HCT) used for?
It is FDA-approved to treat high blood pressure (hypertension). By lowering blood pressure, it also helps reduce the long-term risk of cardiovascular events such as stroke and heart attack. It combines olmesartan, an ARB that relaxes blood vessels, with hydrochlorothiazide, a diuretic that removes extra salt and fluid. It is not used as an initial treatment; it is typically prescribed when blood pressure is not controlled on one of the components alone.
Is olmesartan/hydrochlorothiazide available as a generic?
Yes. Olmesartan medoxomil / hydrochlorothiazide is the generic equivalent of the brand-name product Benicar HCT. The generic contains the same active ingredients and usually costs much less than the brand. Prices still vary by pharmacy, so it is worth comparing before you fill.
What are the most common side effects of olmesartan and hydrochlorothiazide?
Possible side effects include dizziness or lightheadedness from lowered blood pressure, along with effects from the hydrochlorothiazide component such as electrolyte imbalances (low potassium, sodium, or magnesium), higher uric acid or gout, higher blood sugar, and increased sun sensitivity. Less common but serious risks include kidney problems, high potassium, and a rare severe intestinal condition linked to olmesartan that causes chronic diarrhea and weight loss. Contact your provider if you notice concerning symptoms.
Why can't you take olmesartan-hydrochlorothiazide during pregnancy?
This medicine carries a boxed warning for fetal toxicity. Drugs that act on the renin-angiotensin system, like olmesartan, can cause serious injury or death to a developing baby. Because of this, it should not be used during pregnancy and should be stopped as soon as a pregnancy is detected. Tell your provider right away if you are pregnant or planning to become pregnant so they can switch you to a safer option.
What is the difference between Benicar and Benicar HCT?
Benicar contains only olmesartan medoxomil, the ARB. Benicar HCT contains olmesartan plus hydrochlorothiazide, a diuretic, in one pill. Benicar HCT is used when blood pressure needs more control than the ARB alone provides. Both are available as lower-cost generics.
How much does Olmesartan Medoxomil-Hctz cost without insurance?
The price of Olmesartan Medoxomil-Hctz without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Olmesartan Medoxomil-Hctz?
Common side effects of Olmesartan Medoxomil-Hctz may include: Change in how much or how often you urinate, bloody or cloudy urine, Confusion, weakness, muscle twitching, Fast, slow, or uneven heartbeat, chest pain, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Dry mouth, increased thirst, muscle cramps, nausea, vomiting. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Olmesartan Medoxomil-Hctz?
Generic versions may be available for Olmesartan Medoxomil-Hctz. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Olmesartan Medoxomil-Hctz on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Olmesartan Medoxomil-Hctz?
The cheapest pharmacy for Olmesartan Medoxomil-Hctz depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Olmesartan Medoxomil-Hctz near you.

Olmesartan Medoxomil-Hctz Coupons & Prices

Olmesartan Medoxomil-HCTZ 40-25MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Olmesartan Medoxomil-Hctz Tablet — prescription drug image
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Looking for an olmesartan-medoxomil-hctz coupon? This medication is the generic version of Benicar HCT, a fixed-dose combination of olmesartan medoxomil (an angiotensin II receptor blocker, or ARB) and hydrochlorothiazide (a thiazide diuretic) used to treat high blood pressure. Because it is available as a generic, the cash price is already relatively low, but what you actually pay can vary widely from one pharmacy to the next. Enter your ZIP above to compare today's price across more than 60,000 U.S. pharmacies and find a discount coupon you can use at the counter, even without insurance.

What is olmesartan-hydrochlorothiazide and how does it work?

Olmesartan medoxomil / hydrochlorothiazide is a combination blood pressure medication. Olmesartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels so blood can flow more easily, while hydrochlorothiazide is a thiazide diuretic ("water pill") that helps your body remove extra salt and fluid. Together they lower blood pressure and, over time, help reduce the risk of cardiovascular events such as stroke and heart attack.

This combination is FDA-approved for high blood pressure (hypertension), but it is not used as a first, or starting, treatment. Doctors typically prescribe it when blood pressure is not well controlled on olmesartan or hydrochlorothiazide alone, or as a convenient single pill for patients already taking both components separately. This is general information, not medical advice; your provider decides whether this medicine is right for you.

How much does generic olmesartan-hydrochlorothiazide cost, and how to save

Olmesartan-hydrochlorothiazide is available as a generic, which is the main reason it usually costs far less than the brand-name version, Benicar HCT. Even so, cash prices are not the same everywhere. The price for the exact same pills and strength can differ significantly between two pharmacies in the same town, so comparing before you fill is the single best way to keep your out-of-pocket cost down.

Rx.com compares live prices across more than 60,000 pharmacies so you can see where this medication is cheapest near you. Enter your ZIP above to see today's price and pull up a free discount coupon you can show at the pharmacy, no insurance required. If you have insurance, it is still worth comparing, because a coupon price is sometimes lower than a copay.

Related medications and alternatives

If you are comparing options, it can help to look at both the brand equivalent and other ARB-plus-diuretic combinations. The brand-name version of this exact medicine is Benicar HCT. Other closely related choices include:

Only your prescriber can decide which medication and dose fit your situation. Use the price tools above to compare the cash price of each option side by side.

Safety information you should know

This medicine carries a boxed warning for fetal toxicity: drugs that act on the renin-angiotensin system can cause serious injury or death to an unborn baby. It should not be used during pregnancy, and it should be stopped as soon as pregnancy is detected. Talk to your provider right away if you are pregnant or planning to become pregnant.

Other risks to be aware of include low blood pressure (especially if you are dehydrated or on a low-salt diet), high potassium, and reduced kidney function, particularly if combined with NSAID pain relievers or other blood-pressure drugs that act on the same system. The hydrochlorothiazide portion can cause electrolyte imbalances (such as low potassium, low sodium, or low magnesium), raised uric acid or gout, higher blood sugar, sun sensitivity, and, rarely, sudden vision changes or eye pressure problems; it may also increase the risk of non-melanoma skin cancer. A rare but serious side effect linked to olmesartan is a severe, sprue-like intestinal problem causing chronic diarrhea and weight loss. This is not a complete list. Tell your doctor about all the medicines you take, and contact your provider or pharmacist with any questions or concerning symptoms.

Sources & accuracy

This Olmesartan Medoxomil-Hctz information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Olmesartan Medoxomil-Hctz on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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