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Oxycodone Hcl Tablet — prescription drug image

Oxycodone Hcl

oxyCODONE HCl 5MG

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What is Oxycodone Hcl?

Roxicodone is a prescription medication used to treat patients with moderate to severe pain. Oxycodone is the generic version of Roxicodone. Roxicodone costs around $210 for a supply of 120, 5 mg tablets, but luckily there are ways to save money. You can use our Rx.com Roxicodone savings card to save significantly on the retail price at participating pharmacies near you.

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What is Oxycodone Hcl ?

Roxicodone is a prescription medication used to treat patients with moderate to severe pain. Oxycodone is the generic version of Roxicodone. Roxicodone costs around $210 for a supply of 120, 5 mg tablets, but luckily there are ways to save money. You can use our Rx.com Roxicodone savings card to save significantly on the retail price at participating pharmacies near you.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, seeing or hearing things that are not there
  • Extreme dizziness or weakness, shallow breathing, slow heartbeat, sweating, cold or clammy skin, seizures
  • Blue lips, fingernails, or skin, trouble breathing
  • Worsening of pain, increased sensitivity to pain
  • Lightheadedness, dizziness, fainting
  • Changes in skin color, dark freckles, cold feeling, tiredness, weight loss
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, low blood pressure, lung disease or breathing problems (including asthma, COPD, sleep apnea), scoliosis, an enlarged prostate, trouble urinating or swallowing, thyroid problems, Addison disease, gallbladder or pancreas problems, or digestion problems. Tell your doctor if you have a history of head injury, brain tumor, mental health problems, seizures, or alcohol or drug addiction.
  • This medicine may cause the following problems:High risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Sleep-related breathing problems (including sleep apnea, sleep-related hypoxemia)Worsening of painAdrenal gland problemsLow blood pressureSerotonin syndrome, when used with certain medicinesSeizures
  • This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Sit or lie down if you feel dizzy. Stand up carefully.
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation. Drink plenty of liquids to help avoid constipation.
Is oxycodone HCl the same as OxyContin?
They contain the same active ingredient, oxycodone, but they are not identical products. "Oxycodone HCl" refers to oxycodone hydrochloride in general, most often the immediate-release tablets, capsules, or oral solution used for moderate-to-severe pain. OxyContin is a specific extended-release brand designed for around-the-clock, long-term pain management. Your prescriber chooses the form based on your needs.
How long does immediate-release oxycodone take to work and how long does it last?
Immediate-release oxycodone is used for moderate-to-severe pain and is taken as needed or on a schedule your prescriber sets, while extended-release forms are meant for continuous around-the-clock coverage. Timing and dosing vary by person and product, so follow the exact instructions on your label and ask your pharmacist or doctor if you are unsure when to take your next dose.
Is oxycodone stronger than hydrocodone?
Oxycodone and hydrocodone are both opioid pain relievers and are often used for similar levels of pain. Comparing their strength is not straightforward because it depends on the dose, the formulation, and the individual patient. Only your prescriber can decide which opioid and dose are appropriate for you, and you should never substitute one for the other on your own.
Can you become addicted to oxycodone?
Yes. Oxycodone carries an FDA boxed warning for the risk of addiction, abuse, and misuse, which can lead to overdose and death, and it is a Schedule II controlled substance. Physical dependence can also develop even when the medicine is taken as prescribed, and stopping suddenly can cause withdrawal. Take it exactly as directed and talk with your provider about any concerns.
What should you avoid while taking oxycodone?
Avoid alcohol and do not combine oxycodone with benzodiazepines or other central nervous system depressants unless your doctor specifically directs it, because the combination can cause profound sedation, dangerously slowed breathing, coma, or death. Certain medications that affect the CYP3A4 enzyme can also cause dangerous interactions. Tell your doctor and pharmacist about every medicine and supplement you take, and store oxycodone securely away from children.
How much does Oxycodone Hcl cost without insurance?
The price of Oxycodone Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 54% off retail prices with a free Rx.com coupon.
What are the common side effects of Oxycodone Hcl?
Common side effects of Oxycodone Hcl may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, seeing or hearing things that are not there, Extreme dizziness or weakness, shallow breathing, slow heartbeat, sweating, cold or clammy skin, seizures, Blue lips, fingernails, or skin, trouble breathing, Worsening of pain, increased sensitivity to pain. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Oxycodone Hcl?
Generic versions may be available for Oxycodone Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Oxycodone Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Oxycodone Hcl?
The cheapest pharmacy for Oxycodone Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Oxycodone Hcl near you.

Oxycodone Hcl Coupons & Prices

oxyCODONE HCl 5MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Oxycodone Hcl Tablet — prescription drug image
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Oxycodone Hcl 5mg (30)
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Looking for an oxycodone HCl coupon? Oxycodone hydrochloride is the generic form of a Schedule II opioid pain reliever, and because it is already available as a low-cost generic, the cash price you pay can vary widely from one pharmacy to the next. Rx.com compares prices across more than 60,000 pharmacies so you can see today's price and use a free discount coupon at the counter. Enter your ZIP above to see today's price near you.

What is oxycodone HCl and how does it work?

Oxycodone hydrochloride is an opioid analgesic (a narcotic pain reliever) that works as a mu-opioid receptor agonist, changing the way your brain and nervous system respond to pain. It is FDA-approved for the management of acute or chronic pain that is severe enough to require an opioid and for which other treatments are inadequate. Because of its serious risks, it is reserved for patients whose non-opioid options are ineffective or not tolerated.

Oxycodone HCl comes in two main forms. Immediate-release versions (tablets, capsules, and oral solution) are used for moderate-to-severe pain and are sold under brand names such as Roxicodone, Oxaydo, RoxyBond, and OxyIR. Extended-release versions, including OxyContin and Xtampza ER, are designed for around-the-clock, long-term pain management. This information is educational and is not a substitute for guidance from your doctor or pharmacist.

Oxycodone HCl cost without insurance and how to save

Oxycodone hydrochloride is available as a generic, which typically keeps it among the lower-cost prescription options. Even so, the cash price is not the same everywhere: pharmacies set their own prices, so the amount you pay for the same strength and quantity can differ substantially from store to store. That is exactly why comparing before you fill matters.

Rx.com checks live prices across more than 60,000 pharmacies and provides a free discount coupon you can use whether or not you have insurance. There is no manufacturer copay card for generic oxycodone HCl, so a pharmacy-price comparison is usually the most reliable way to lower your cost. Enter your ZIP above to see today's price and print or show your coupon at the pharmacy.

Related opioids and alternatives

Oxycodone HCl is one of several opioid pain medications, and your prescriber chooses among them based on your condition, response, and risk factors. It is often confused with or compared to combination and single-ingredient opioids. Related medications you can compare on Rx.com include:

Never switch opioids or change your dose on your own. Only your provider can determine which medication and strength are appropriate for you.

Important safety information

Oxycodone HCl is a Schedule II controlled substance and carries FDA boxed warnings. These include the risk of addiction, abuse, and misuse that can lead to overdose and death; life-threatening respiratory depression, especially when starting the medicine or increasing the dose; and the danger that accidental ingestion, especially by a child, can be fatal. Prolonged use during pregnancy can cause neonatal opioid withdrawal syndrome. There is a potentially fatal interaction with certain CYP3A4 inhibitors and inducers, and combining oxycodone with benzodiazepines, alcohol, or other central nervous system depressants can cause profound sedation, respiratory depression, coma, and death. A REMS program applies.

More common side effects include constipation, sedation, low blood pressure, and, with long-term use, adrenal insufficiency. Physical dependence can develop, and stopping abruptly can trigger withdrawal, so any dose changes should be managed by your prescriber. This is general information, not medical advice. Talk with your doctor or pharmacist about your specific situation, other medicines you take, and how to store and dispose of this medication safely.

Sources & accuracy

This Oxycodone Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Oxycodone Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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