Phentermine-Topiramate Er Coupons & Prices

Looking for a Qsymia coupon? Qsymia (phentermine and topiramate extended-release) is a brand-name, once-daily prescription capsule for chronic weight management. An FDA-approved generic phentermine/topiramate extended-release capsule is now on the US market, but the brand can still carry a high cash price, and not everyone is switched to the generic automatically. Rx.com offers a free cash-price coupon that is accepted at most major pharmacies and can be used on the brand or the generic. Enter your ZIP above to see today's price at pharmacies near you.

What is Qsymia and how does it work?

Qsymia is a combination capsule that pairs two long-used medicines: phentermine, a sympathomimetic amine that helps curb appetite, and topiramate extended-release, an antiseizure medicine that can reduce cravings and increase the feeling of fullness. Together they support weight loss when used as an add-on to a reduced-calorie diet and increased physical activity. It is taken once daily, usually in the morning, and is typically started at a low dose and increased gradually.

Qsymia is FDA-approved for chronic weight management in adults with a starting BMI of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) who also have at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol. It is also approved for children aged 12 and older who have a BMI in the 95th percentile or greater for their age and sex. It is not intended for cosmetic weight loss. Because it contains phentermine, Qsymia is a Schedule IV controlled substance.

Qsymia cost: brand, generic, and the Rx.com cash coupon

The manufacturer, Vivus, runs an official Qsymia savings program (details are on the brand's own website, qsymia.com). Manufacturer copay cards like this are generally limited to people with commercial (private) insurance and cannot be used if you have Medicare, Medicaid, or other government coverage, or if you are paying cash. Program terms and eligibility can change, so check the current rules directly.

There is now an FDA-approved generic of this phentermine/topiramate extended-release combination on the US market. The first generic was approved in June 2024 and launched in May 2025, and it is marketed by manufacturers including Teva (Actavis) and Dr. Reddy's in all four strengths. Because the generic is bioequivalent and typically costs far less than the brand, asking your prescriber and pharmacist about the generic is usually the single biggest cost-savings lever for this medicine. Like the brand, the generic is dispensed through the shared REMS program.

If you are uninsured, on Medicare, or the manufacturer card is declined, the Rx.com cash coupon is a straightforward alternative on either the brand or the generic. It sets a discounted cash price you can show at the pharmacy counter, and it works whether or not you have insurance. Enter your ZIP above to compare today's cash price at pharmacies near you.

Qsymia alternatives and how they compare

Qsymia is one of several prescription options for chronic weight management, and they work in different ways. The lowest-cost version of Qsymia's own formula is usually its FDA-approved generic (phentermine/topiramate extended-release), so ask your prescriber whether the generic is right for you. If the combination itself is not a good fit, a prescriber may consider:

• Contrave - a naltrexone/bupropion combination pill, another oral once- or twice-daily option.
• Wegovy - a once-weekly semaglutide injection (a GLP-1 medicine).
• Zepbound - a once-weekly tirzepatide injection.
• Saxenda - a once-daily liraglutide injection.
• Phentermine - one of the two active ingredients in Qsymia, available on its own as a short-term appetite suppressant.

Which option is appropriate depends on your health history, other conditions, and how each medicine is taken. This is a decision to make with your prescriber, not a self-serve swap.

Qsymia safety and important warnings

Qsymia carries important FDA warnings. It must not be used during pregnancy because it can harm a developing baby, including an increased risk of oral clefts (cleft lip or cleft palate) when taken in the first trimester. Females who can become pregnant should have a negative pregnancy test before starting and monthly during treatment, and should use effective birth control. For this reason, Qsymia is available only through the restricted Qsymia REMS Program. Because it contains phentermine, it also has a potential for abuse.

Other risks noted on the label include increased heart rate (your pulse should be monitored), mood changes and suicidal thoughts or behavior, trouble with concentration, memory, or confusion, sudden vision problems from acute angle-closure glaucoma, metabolic acidosis, kidney stones, and low blood sugar in people with diabetes taking insulin or certain other medicines. Do not stop Qsymia abruptly, as this can raise the risk of seizures. Qsymia should not be used if you have glaucoma or an overactive thyroid, or within 14 days of a MAO inhibitor. This is a summary, not medical advice - talk with your doctor or pharmacist about your full history and current medicines before starting or stopping Qsymia.