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Brimonidine Tartrate

Brimonidine Tartrate 5ML of 0.2%

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What is Brimonidine Tartrate?

Alphagan P is used to treat ocular hypertension or open-angle glaucoma. The generic version of Alphagan P is Brimonidine ophthalmic. On average Combigan is priced at about $212 for 5 mL, 0.1% ophthalmic solution. Luckily, you can use our Rx.com savings offer to receive an Alphagan P discount of up to 80% off the retail price at participating pharmacies near you.

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What is Brimonidine Tartrate ?

Alphagan P is used to treat ocular hypertension or open-angle glaucoma. The generic version of Alphagan P is Brimonidine ophthalmic. On average Combigan is priced at about $212 for 5 mL, 0.1% ophthalmic solution. Luckily, you can use our Rx.com savings offer to receive an Alphagan P discount of up to 80% off the retail price at participating pharmacies near you.
  • Severe eye irritation or pain
  • Fast, slow, or pounding heartbeat.
  • Red, painful, or swollen eyelids
  • Redness in the white part of the eyes or inside of the eyelids
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision or other changes in vision
  • Burning, stinging, dry, or itching eyes
  • Eye discharge or excessive tearing
  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease, orthostatic hypotension (low blood pressure when standing up), blood vessel disease (including Raynaud phenomenon, thromboangiitis obliterans), depression, or if you have had a heart attack or stroke.
  • Alphagan® P may make you lightheaded, dizzy, or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.
  • Redness in the white part of the eyes or inside of the eyelids.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Red, painful, or swollen eyelids.
  • Severe eye irritation or pain.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
What is brimonidine tartrate used for?
As an eye drop, brimonidine tartrate lowers pressure inside the eye in people with open-angle glaucoma or ocular hypertension. Other forms of the same drug include a topical gel (Mirvaso) approved for the persistent facial redness of rosacea in adults and a low-dose over-the-counter drop (Lumify) for relieving everyday eye redness. Use the specific product your provider prescribed.
Is brimonidine tartrate the same as Alphagan or Lumify?
They share the same active ingredient, brimonidine tartrate, but they are not interchangeable. Alphagan P is the prescription eye drop for glaucoma and ocular hypertension, and generic brimonidine tartrate matches it. Lumify is a much lower-dose (0.025%) over-the-counter drop made only to relieve eye redness, not to treat glaucoma.
How long does it take for brimonidine eye drops to work?
Brimonidine begins lowering eye pressure within a couple of hours of a dose, with the effect building over the treatment course. Because you usually cannot feel changes in eye pressure, your eye doctor confirms it is working through regular pressure checks. Keep using the drops exactly as prescribed even if you feel no difference.
What are the most common side effects of brimonidine tartrate?
The most common effects are drowsiness or fatigue, dizziness, dry mouth, and eye symptoms such as redness, itching, or an allergic reaction (follicular conjunctivitis). These are often mild, but tell your provider if they are bothersome or persistent, and seek help right away for any serious reaction.
Can brimonidine gel make rosacea redness worse?
Yes, some people using the topical gel for rosacea notice a paradoxical worsening of facial redness, rebound flushing, or intensified erythema, sometimes hours after applying it. If this happens, stop using it and contact your provider to discuss whether to continue or try a different approach.
How much does Brimonidine Tartrate cost without insurance?
The price of Brimonidine Tartrate without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 59% off retail prices with a free Rx.com coupon.
What are the common side effects of Brimonidine Tartrate?
Common side effects of Brimonidine Tartrate may include: Severe eye irritation or pain, Fast, slow, or pounding heartbeat., Red, painful, or swollen eyelids, Redness in the white part of the eyes or inside of the eyelids, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Brimonidine Tartrate?
Generic versions may be available for Brimonidine Tartrate. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Brimonidine Tartrate on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Brimonidine Tartrate?
The cheapest pharmacy for Brimonidine Tartrate depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Brimonidine Tartrate near you.

Brimonidine Tartrate Coupons & Prices

Brimonidine Tartrate 5ML of 0.2%

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Brimonidine Tartrate Bottle — prescription drug image
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a brimonidine tartrate coupon? Brimonidine tartrate is the low-cost generic behind brand eye drops like Alphagan P, so you rarely need to pay brand prices. Cash prices still swing widely from one pharmacy to the next, which is exactly why comparing matters. Rx.com checks live prices across more than 60,000 pharmacies so you can enter your ZIP above to see today's price near you before you fill.

What is brimonidine tartrate and how does it work?

Brimonidine tartrate is an alpha-2 adrenergic agonist. As an ophthalmic (eye) solution, such as Alphagan P and its generics, it lowers pressure inside the eye (intraocular pressure) in people with open-angle glaucoma or ocular hypertension. It does this by reducing how much fluid the eye makes and helping fluid drain, which helps protect the optic nerve over time.

The same active ingredient appears in a few other products. A topical gel 0.33% (Mirvaso) is approved to treat the persistent facial redness of rosacea in adults, and a low-dose 0.025% eye drop (Lumify) is sold over the counter to relieve everyday eye redness. Doctors also sometimes use brimonidine drops short-term, off-label, to blunt pressure spikes after laser eye procedures. Always use the specific product your provider prescribed for its intended purpose.

How much does generic brimonidine tartrate cost without insurance?

Because brimonidine tartrate is available as a generic, it is generally an affordable medication even if you are paying cash. The catch is that the price for the exact same bottle can vary a lot depending on which pharmacy you walk into, so it pays to compare rather than assume your usual pharmacy has the best deal.

Rx.com compares live cash prices across more than 60,000 pharmacies. Enter your ZIP above to see today's price near you, then show the coupon at the counter. If you have been prescribed a brand version such as Mirvaso, the manufacturer (Galderma) also offers a savings program on its official website; eligibility and terms vary, so check the details directly.

Brimonidine tartrate alternatives and related products

Brimonidine comes in several forms and is often compared with other glaucoma and redness treatments. Related options include:

  • Alphagan P — the brand ophthalmic solution that generic brimonidine tartrate matches.
  • Combigan — a combination eye drop pairing brimonidine with timolol for glaucoma.
  • Lumify — a low-dose over-the-counter brimonidine drop for relieving eye redness.
  • Mirvaso — the topical gel for facial redness from rosacea.
  • Other glaucoma medicines your provider may consider, such as latanoprost, timolol, or dorzolamide-timolol.

Your eye doctor chooses among these based on your eye pressure, response, and tolerance. Comparing prices on whichever one you are prescribed can still save you money.

Safety and side effects to know

Common side effects of brimonidine include drowsiness or fatigue, dizziness, dry mouth, and eye reactions such as redness, itching, or follicular conjunctivitis. Ophthalmic brimonidine should not be used in newborns or infants under 2 years and is used with caution in young children because of the risk of serious effects like slowed breathing, low heart rate, low blood pressure, and low body temperature. With the topical gel for rosacea, some people notice a paradoxical worsening of redness or rebound flushing.

Use extra caution if you have severe cardiovascular disease, low blood pressure on standing, reduced blood flow to the brain or heart, Raynaud's, or liver or kidney problems. Brimonidine can add to the sedating effects of alcohol and other CNS depressants, and it may interact with MAO inhibitors, tricyclic antidepressants, beta-blockers, and blood pressure medicines. There is no boxed warning. This is general information, not medical advice — talk with your doctor or pharmacist about your full medication list and health history before starting or changing treatment.

Sources & accuracy

This Brimonidine Tartrate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Brimonidine Tartrate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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