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Hyoscyamine Sulfate Tablet — prescription drug image

Hyoscyamine Sulfate

Hyoscyamine Sulfate 0.125MG

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What is Hyoscyamine Sulfate?

Oscimin is used to treat the symptoms of nasal congestions, mild dysenteries, diarrhea and diverticulitis. It is used with pain medications to treat the symptoms of biliary and renal colic. It is also used to treat other conditions as prescribed by your doctor. The generic version of Oscimin is Hyoscyamine. On average, Oscimin is priced at about $19 for a supply of 15, 0.125 mg sublingual tablets. You can use our free Singlecare savings card to receive an Oscimin discount of up to 80% at a local pharmacy that participates with Singlecare.

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What is Hyoscyamine Sulfate ?

Oscimin is used to treat the symptoms of nasal congestions, mild dysenteries, diarrhea and diverticulitis. It is used with pain medications to treat the symptoms of biliary and renal colic. It is also used to treat other conditions as prescribed by your doctor. The generic version of Oscimin is Hyoscyamine. On average, Oscimin is priced at about $19 for a supply of 15, 0.125 mg sublingual tablets. You can use our free Singlecare savings card to receive an Oscimin discount of up to 80% at a local pharmacy that participates with Singlecare.

  • Blurred vision that does not go away
  • Fast heartbeat, dizziness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Unusual behavior, such as confusion, memory loss, anxiety, trouble sleeping, or hallucinations
  • Tell your doctor if you are pregnant or breastfeeding, or if you have glaucoma, trouble urinating, myasthenia gravis, overactive thyroid, kidney disease, high blood pressure, heart rhythm problems, heart disease, or autonomic neuropathy. Tell your doctor about all digestion problems, including colitis, reflux disease (GERD), blocked intestines, or gastric ulcer.
  • This medicine may cause you to sweat less and overheat. Avoid hot temperatures.
  • This medicine may make you dizzy or drowsy or give you blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is hyoscyamine sulfate used for?

Hyoscyamine sulfate is an antispasmodic used to control symptoms of gastrointestinal disorders by relaxing the gut and reducing stomach acid and secretions. It is commonly used for irritable bowel syndrome (IBS), functional GI and spasm disorders, and as add-on therapy for peptic ulcer disease and diverticulitis. It is also used for bladder and urinary spasms and cystitis, for biliary and kidney-stone (renal) colic, for pancreatitis, for infant colic, and to reduce drooling, excess saliva, and runny-nose secretions.

Is hyoscyamine sulfate a controlled substance?

No. Hyoscyamine sulfate is not a controlled substance and is not on any DEA schedule. It is a prescription antispasmodic, but it does not carry the controlled-substance restrictions that apply to drugs with abuse potential.

What are the side effects of hyoscyamine?

The most common side effects are anticholinergic ones: dry mouth, blurred vision, constipation, trouble urinating, drowsiness or dizziness, a faster heartbeat, and reduced sweating that can lead to overheating in hot weather. It can also cause confusion, especially in older adults. Very high doses can cause an anticholinergic overdose with high fever, delirium, and agitation. Contact your doctor or pharmacist if side effects bother you or do not go away.

How quickly does hyoscyamine work and how long does it last?

This can vary by the form you take. Immediate-release tablets, including the sublingual and orally disintegrating versions, are designed to act relatively quickly and are typically dosed several times a day, while the extended-release form (Levbid) is made to work over a longer period so it can be taken less often. Follow the dosing schedule your prescriber gives you, and ask your pharmacist if you are unsure which form you have.

Who should not take hyoscyamine sulfate?

Hyoscyamine should not be used by people with angle-closure glaucoma, obstructive bowel disease (such as pyloric stenosis or paralytic ileus), bladder-neck or urinary obstruction, myasthenia gravis, severe ulcerative colitis or toxic megacolon, or unstable heart conditions or active bleeding. Older adults should use it cautiously because it can cause confusion. Give your doctor and pharmacist your full medical history and medication list before starting it.

How much does Hyoscyamine Sulfate 0.125MG cost without insurance?
The price of Hyoscyamine Sulfate 0.125MG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Hyoscyamine Sulfate 0.125MG?
Common side effects of Hyoscyamine Sulfate 0.125MG may include: Blurred vision that does not go away, Fast heartbeat, dizziness, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Unusual behavior, such as confusion, memory loss, anxiety, trouble sleeping, or hallucinations. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Hyoscyamine Sulfate 0.125MG?
Generic versions may be available for Hyoscyamine Sulfate 0.125MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Hyoscyamine Sulfate 0.125MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Hyoscyamine Sulfate 0.125MG?
The cheapest pharmacy for Hyoscyamine Sulfate 0.125MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Hyoscyamine Sulfate 0.125MG near you.

Hyoscyamine Sulfate Coupons & Prices

Hyoscyamine Sulfate 0.125MG

Prescriptions & Refills
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Hyoscyamine Sulfate Tablet — prescription drug image
Prescription
Hyoscyamine Sulfate 0.125mg (30)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Hyoscyamine Sulfate prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
0.125mg · Tablet Sublingual 30 $25.78

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a hyoscyamine sulfate coupon? Hyoscyamine sulfate is an inexpensive generic antispasmodic sold under brand names like Levsin, Levbid, Anaspaz, and NuLev, but the cash price you pay can vary a lot from one pharmacy to the next. Rx.com compares live prices across more than 60,000 U.S. pharmacies so you can see today's lowest cost and get a free discount coupon in seconds. Enter your ZIP above to see the current price near you.

What is hyoscyamine sulfate and how does it work?

Hyoscyamine sulfate is an anticholinergic (antispasmodic) medicine in the belladonna alkaloid family. It works by relaxing the smooth muscle of the gut and urinary tract and by reducing stomach acid and other body secretions, which calms cramping and spasms. Doctors commonly prescribe it for gastrointestinal conditions such as irritable bowel syndrome (IBS), functional GI and spasm disorders, and as add-on therapy for peptic ulcer disease and diverticulitis. It is also used for bladder and urinary spasms and cystitis, for biliary and renal (kidney-stone) colic, for pancreatitis, for infant colic, and to reduce excess saliva, drooling, and runny-nose secretions.

It comes in several forms, including regular tablets, orally disintegrating tablets (NuLev), sublingual tablets that dissolve under the tongue (Levsin/SL), and extended-release tablets (Levbid). This is general information, not medical advice; your prescriber will choose the form and dose that fits your condition.

Hyoscyamine sulfate cost and how to save without insurance

Hyoscyamine sulfate is available as a generic, so it is already one of the lower-cost prescription options in its class. Even so, the cash price is not the same everywhere, and shoppers without insurance are often surprised by how widely two nearby pharmacies can differ for the exact same tablet and quantity. That is why comparing before you fill matters. There is no manufacturer savings card for this generic, so a free pharmacy discount coupon is usually the most reliable way to lower an out-of-pocket cost.

Rx.com pulls live pricing from more than 60,000 pharmacies and shows the current amount along with a coupon you can use at the counter. Because prices update in real time, we don't list a fixed dollar figure here. Enter your ZIP above to see today's price near you, and check both the immediate-release and extended-release (Levbid) versions if your prescription allows, since costs can differ by form.

Related medicines and alternatives

Hyoscyamine is one of several antispasmodic and anticholinergic drugs. If you are comparing options with your prescriber, related medicines include dicyclomine, another common gut antispasmodic, and the brand versions of hyoscyamine itself: Levsin, Levbid, and Anaspaz. Other drugs in the broader anticholinergic family include atropine, scopolamine, and glycopyrrolate for reducing secretions, and oxybutynin for bladder spasms.

Choosing among these depends on your specific condition and health history, so this list is a starting point for a conversation with your doctor or pharmacist, not a recommendation to switch. Whichever medicine you are prescribed, you can compare its price on Rx.com to find the lowest cash cost near you.

Safety and side effects

Hyoscyamine has no FDA boxed warning, but its anticholinergic action causes predictable side effects: dry mouth, blurred vision, constipation, difficulty urinating, drowsiness or dizziness, faster heartbeat, and reduced sweating that can make you overheat in hot weather. It can also cause confusion, particularly in older adults, and it appears on the Beers list of medications to use with caution in the elderly. It can interact with alcohol, other anticholinergic drugs, and sedatives, so tell your pharmacist about everything you take.

Hyoscyamine is not appropriate for everyone. It is contraindicated in angle-closure glaucoma, obstructive bowel disease (such as pyloric stenosis or paralytic ileus), bladder-neck or urinary obstruction, myasthenia gravis, severe ulcerative colitis or toxic megacolon, and in unstable heart conditions or active bleeding. This is general information and not medical advice. Talk with your doctor or pharmacist about your full history, and seek care promptly if you develop high fever, severe confusion, or a racing heartbeat.

Sources & accuracy

This Hyoscyamine Sulfate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Hyoscyamine Sulfate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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