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Mirtazapine

Mirtazapine 15MG

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What is Mirtazapine?

Mirtazapine treats depression. Mirtazapine is the generic version of the drugs Remeron and Remeron SolTab. For a supply of 30 oral tablets of Mirtazapine 15 mg, the average cost is $212. A quick and easy way to save on your Mirtazapine cost is to use Rx.com’s free coupon card when purchasing your prescription at your local pharmacy.

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What is Mirtazapine ?

Mirtazapine treats depression. Mirtazapine is the generic version of the drugs Remeron and Remeron SolTab. For a supply of 30 oral tablets of Mirtazapine 15 mg, the average cost is $212. A quick and easy way to save on your Mirtazapine cost is to use Rx.com’s free coupon card when purchasing your prescription at your local pharmacy.
  • Fever, chills, cough, sore throat, body aches
  • Eye pain, vision changes, seeing halos around lights
  • Thoughts of hurting yourself or others, worsening depression, unusual behaviors
  • Confusion, weakness, muscle twitching
  • Feeling more excited or energetic than usual
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, nausea, vomiting, diarrhea, seeing or hearing things that are not there
  • Blistering, peeling, red skin rash
  • For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, glaucoma, high cholesterol, heart or blood vessel disease, heart rhythm problems (including QT prolongation), or a history of seizures, heart attack, or stroke. Tell your doctor if you have phenylketonuria.
  • This medicine may cause the following problems:Serotonin syndrome (may be life-threatening when used with certain other medicines)Serious skin reaction, including drug reaction with eosinophilia and systemic symptoms (DRESS)
  • This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is mirtazapine used for?
Mirtazapine is FDA-approved to treat major depressive disorder (MDD) in adults. It is a tetracyclic antidepressant and is the generic form of Remeron. It is not approved for use in children.
Does mirtazapine cause weight gain?
Yes, increased appetite and weight gain are among the most common side effects of mirtazapine. If weight gain is a concern for you, discuss it with your doctor, who can weigh the benefits and drawbacks and consider other options.
How long does it take for mirtazapine to work?
Some effects, such as improved sleep and appetite, may be noticed fairly early because mirtazapine is sedating. However, the full antidepressant benefit for mood often takes several weeks. Keep taking it as prescribed and follow up with your provider, even if you do not feel a difference right away.
Is mirtazapine good for sleep and anxiety?
Mirtazapine is often sedating, and some people find it helps with sleep, but it is only FDA-approved to treat major depressive disorder in adults. Its use for sleep or anxiety is not an approved indication, so any such use should be directed and monitored by your doctor.
What are the side effects of mirtazapine?
Common side effects include drowsiness, increased appetite and weight gain, dry mouth, dizziness, and constipation. Rare but serious risks include serotonin syndrome, a drop in infection-fighting white blood cells, QT prolongation, glaucoma, low sodium levels, and higher cholesterol. Antidepressants also carry a boxed warning about suicidal thoughts in people under 25. Contact your doctor if you notice anything concerning.
How much does Mirtazapine cost without insurance?
The price of Mirtazapine without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 76% off retail prices with a free Rx.com coupon.
What are the common side effects of Mirtazapine?
Common side effects of Mirtazapine may include: Fever, chills, cough, sore throat, body aches, Eye pain, vision changes, seeing halos around lights, Thoughts of hurting yourself or others, worsening depression, unusual behaviors, Confusion, weakness, muscle twitching, Feeling more excited or energetic than usual. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Mirtazapine?
Generic versions may be available for Mirtazapine. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Mirtazapine on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Mirtazapine?
The cheapest pharmacy for Mirtazapine depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Mirtazapine near you.

Mirtazapine Coupons & Prices

Mirtazapine 15MG

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Mirtazapine Tablet — prescription drug image
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a mirtazapine coupon? Mirtazapine is the low-cost generic version of Remeron, a prescription antidepressant approved to treat major depressive disorder. Because it has been generic for years, the cash price is already modest, but what you actually pay can vary a lot from one pharmacy to the next. Rx.com compares live prices across more than 60,000 U.S. pharmacies so you can see today's lowest price near you and bring a free discount coupon with you. Enter your ZIP above to see today's price on mirtazapine.

What is mirtazapine and how does it work?

Mirtazapine is a tetracyclic antidepressant, sometimes called a noradrenergic and specific serotonergic antidepressant (NaSSA). It is the active ingredient in the brand-name drug Remeron and Remeron SolTab. It works differently from common SSRIs by increasing the activity of two brain chemicals, norepinephrine and serotonin, which help regulate mood. It is FDA-approved to treat major depressive disorder (MDD) in adults and is taken once daily, usually at bedtime because it tends to be sedating.

Mirtazapine is available as a standard tablet and as an orally disintegrating tablet (mirtazapine ODT) that dissolves on the tongue. It is not approved for use in children. Your doctor will decide whether it is the right fit based on your symptoms and health history.

Mirtazapine cost and coupon savings without insurance

Mirtazapine is a generic medication, so it is generally one of the more affordable antidepressants to buy, even without insurance. Still, cash prices are not the same everywhere. Two pharmacies in the same town can charge noticeably different amounts for the exact same prescription, which is why comparing before you fill is worth it. A free Rx.com discount coupon can often lower the cash price at the register, and no insurance is required to use one.

To find your price, enter your ZIP above to see today's price at pharmacies near you, then show the coupon to the pharmacist. Because the brand-name version (Remeron) is usually much more expensive than generic mirtazapine, ask your prescriber or pharmacist whether the generic is appropriate for you.

Mirtazapine alternatives and related medications

Mirtazapine is one of several antidepressants your doctor may consider. Others work through different mechanisms and have different side-effect profiles, so the best choice depends on your individual situation. Related and commonly compared options include:

  • Remeron — the brand-name version of mirtazapine itself.
  • Sertraline — an SSRI antidepressant (generic for Zoloft).
  • Bupropion — an antidepressant that is less likely to cause weight gain or sedation.
  • Trazodone — another antidepressant that is often sedating.
  • Mirtazapine ODT — the dissolvable tablet form.

Never switch or stop an antidepressant on your own. Talk with your provider about which medication and dose are right for you.

Mirtazapine safety and side effects

Mirtazapine carries a boxed warning: antidepressants can increase the risk of suicidal thoughts and behaviors in children, adolescents, and young adults under 25, especially early in treatment or when the dose changes. Anyone starting the medication should be watched closely for worsening mood or unusual changes in behavior. Mirtazapine is not approved for children. It is not a controlled substance.

The most common side effects are drowsiness, increased appetite and weight gain, dry mouth, dizziness, and constipation. More serious but less common risks include serotonin syndrome (the risk rises when combined with other serotonergic drugs; MAOIs are contraindicated), a rare drop in infection-fighting white blood cells (tell your doctor about any fever, sore throat, or signs of infection), QT prolongation, angle-closure glaucoma, low sodium levels (more likely in older adults), and increases in cholesterol and triglycerides. Alcohol worsens the sedation, and you should not stop the drug abruptly because discontinuation symptoms can occur. This is general information, not medical advice — talk with your doctor or pharmacist about your specific situation.

Sources & accuracy

This Mirtazapine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Mirtazapine on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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