Norethindrone Acet-Ethinyl Est
Norethindrone Acet-Ethinyl Est 21 Tablets
What is Norethindrone Acet-Ethinyl Est?
Microgestin 1/20 is a combination medication that prevents pregnancy in women. Ethinyl estradiol/norethindrone is the generic version of Microgestin 1/20. The average Microgestin 1/20 price is about $109 for a supply of 126, 20 mcg-1 mg oral tablets. However, you can use our free Rx.com coupon card to save significantly on Microgestin 1/20 prices at a participating pharmacy near you.Side Effects
- Heavy vaginal bleeding
- Chest pain or tightness, trouble breathing, coughing up blood
- Rapid weight gain, swelling in your hands, ankles, or feet
Warnings
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you had a baby within 4 weeks before you start using this medicine. Tell your doctor if you have kidney disease, asthma, cervical cancer, diabetes, epilepsy, gallbladder problems, heart or blood vessel disease, high cholesterol, or a family history of breast cancer or depression. Tell your doctor if you smoke, wear contact lenses, or if you will be having a surgery with a prolonged period of inactivity.
- This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsPossible risk of cancer (including cancer of the breast, endometrium, ovaries, or cervix)Liver problemsChanges in visionGallbladder diseaseHigh cholesterol in the bloodHigh blood pressure
- This medicine will not protect you from HIV/AIDS or other sexually transmitted diseases.
- You might have some light bleeding or spotting when you first start using this medicine. This is usually normal and should not last long. However, if you have heavy bleeding or the bleeding lasts more than seven days in a row, call your doctor€™s office.
Prescription savings · · · ·
What is Norethindrone Acet-Ethinyl Est ?
Microgestin 1/20 is a combination medication that prevents pregnancy in women. Ethinyl estradiol/norethindrone is the generic version of Microgestin 1/20. The average Microgestin 1/20 price is about $109 for a supply of 126, 20 mcg-1 mg oral tablets. However, you can use our free Rx.com coupon card to save significantly on Microgestin 1/20 prices at a participating pharmacy near you.- Heavy vaginal bleeding
- Chest pain or tightness, trouble breathing, coughing up blood
- Rapid weight gain, swelling in your hands, ankles, or feet
- Numbness or weakness in your arm or leg, or on one side of your body
- Dark urine or pale stools, loss of appetite, yellow skin or eyes
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Breast lumps, pain, swelling, tenderness, or discharge
- Pain in your lower leg (calf)
- Fast or pounding heartbeat
- Sudden or severe headache, problems with vision, speech, or walking
- Sudden and severe stomach pain, nausea, vomiting, lightheadedness
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you had a baby within 4 weeks before you start using this medicine. Tell your doctor if you have kidney disease, asthma, cervical cancer, diabetes, epilepsy, gallbladder problems, heart or blood vessel disease, high cholesterol, or a family history of breast cancer or depression. Tell your doctor if you smoke, wear contact lenses, or if you will be having a surgery with a prolonged period of inactivity.
- This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsPossible risk of cancer (including cancer of the breast, endometrium, ovaries, or cervix)Liver problemsChanges in visionGallbladder diseaseHigh cholesterol in the bloodHigh blood pressure
- This medicine will not protect you from HIV/AIDS or other sexually transmitted diseases.
- You might have some light bleeding or spotting when you first start using this medicine. This is usually normal and should not last long. However, if you have heavy bleeding or the bleeding lasts more than seven days in a row, call your doctor€™s office.
- Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Norethindrone Acet-Ethinyl Est Coupons & Prices
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Looking for a norethindrone acetate / ethinyl estradiol coupon? This is a generic combination birth control pill sold under many brand names, so it is already one of the lower-cost prescriptions at the pharmacy counter. Even so, the cash price can vary widely from one pharmacy to the next, which is why comparing matters. Enter your ZIP above to see today's price and a free Rx.com discount coupon you can use at more than 60,000 U.S. pharmacies.
What is norethindrone acetate / ethinyl estradiol and how does it work?
Norethindrone acetate / ethinyl estradiol is a combination oral medication that pairs a progestin (norethindrone acetate) with an estrogen (ethinyl estradiol). As a combined oral contraceptive, it is FDA-approved to prevent pregnancy, mainly by stopping ovulation and changing cervical mucus and the uterine lining. Certain lower-dose formulations are also approved to treat moderate acne in women who also want contraception.
Higher-estrogen versions that combine norethindrone acetate with ethinyl estradiol are approved separately for menopausal hormone replacement therapy (HRT) to treat moderate-to-severe hot flashes and vaginal atrophy, and to help prevent postmenopausal osteoporosis. Because the same two ingredients appear in both birth control and HRT products at different doses, it is important to use the exact product your provider prescribed. This medication does not protect against HIV or other sexually transmitted infections.
Cost and savings: what you'll pay without insurance
Because an FDA-approved generic is widely available, norethindrone acetate / ethinyl estradiol is usually inexpensive compared with brand-name birth control. Still, the cash price without insurance is not the same everywhere; two pharmacies in the same town can list very different prices for the identical pill pack. Comparing before you fill is the single easiest way to avoid overpaying.
Rx.com compares prices across more than 60,000 pharmacies and shows you a free discount coupon that works whether or not you have insurance. Enter your ZIP above to see today's price near you. If you are prescribed a brand such as Lo Loestrin Fe, the manufacturer also offers a copay savings program on its official website (loloestrin.com); eligibility and terms vary and generally exclude government insurance, so compare that against the cash coupon price to see which is lower for you.
Related and alternative birth control options
Norethindrone acetate / ethinyl estradiol is the generic behind many familiar brands. If your prescription names a specific brand, you can look up its price directly:
- Lo Loestrin Fe and Loestrin
- Junel Fe and Microgestin Fe
- ethinyl estradiol / norethindrone, a closely related generic combination
Other combined oral contraceptives use different progestins, such as drospirenone / ethinyl estradiol or levonorgestrel / ethinyl estradiol. There is also a progestin-only option, norethindrone, for those who cannot take estrogen. Which option fits you depends on your health history, so any switch should be discussed with your provider. This is general information, not medical advice.
Safety and who should not take it
These products carry a boxed warning: cigarette smoking raises the risk of serious cardiovascular events from combined oral contraceptive use. That risk increases with age and with heavy smoking and is significant in women over 35, who should not use combined oral contraceptives. Combined estrogen/progestin pills also increase the risk of blood clots (venous thromboembolism), stroke, and heart attack, and that risk is higher for people with a history of clots, uncontrolled high blood pressure, migraine with aura, or a known clotting disorder.
Norethindrone acetate / ethinyl estradiol is contraindicated during pregnancy and in people with breast or other estrogen-dependent cancers, undiagnosed abnormal uterine bleeding, or active liver disease. HRT formulations that use these ingredients carry additional warnings for endometrial cancer, probable dementia, and cardiovascular and breast-cancer risks with estrogen-plus-progestin therapy. Talk with your doctor or pharmacist about your personal history before starting, and seek care promptly for warning signs like chest pain, sudden shortness of breath, severe leg pain, or a sudden severe headache. This is not medical advice.
This Norethindrone Acet-Ethinyl Est information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Norethindrone Acet-Ethinyl Est on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.