Paroxetine Mesylate Coupons & Prices

Looking for a paroxetine mesylate coupon? Paroxetine mesylate is a generic selective serotonin reuptake inhibitor (SSRI), sold under the brand names Pexeva and Brisdelle, and a generic version is available. Even as a generic, the cash price can vary widely from one pharmacy to the next, so comparing matters. Rx.com compares prices across more than 60,000 pharmacies so you can find a lower price near you. Enter your ZIP above to see today's price and print or text yourself a free coupon.

What is paroxetine mesylate and how does it work?

Paroxetine mesylate is the mesylate salt of paroxetine, a selective serotonin reuptake inhibitor (SSRI) antidepressant. SSRIs work by increasing the amount of serotonin, a natural chemical messenger, available in the brain. Paroxetine mesylate is marketed under two brand names that have very different FDA-approved uses.

As Pexeva (tablets), it is approved to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, and generalized anxiety disorder (GAD). As Brisdelle (7.5 mg capsules), it is approved specifically for moderate to severe hot flashes associated with menopause and is not indicated for any psychiatric condition. Paroxetine more broadly (including the hydrochloride salt sold as Paxil) is also used off-label for conditions such as social anxiety disorder, PTSD, and PMDD. Your prescriber decides which form and dose is right for you.

How much does generic paroxetine mesylate cost without insurance?

Because paroxetine mesylate is available as a generic, it is generally a lower-cost medication than the brand-name versions. That said, the cash price you pay without insurance can differ significantly depending on which pharmacy you use, even within the same town. That is exactly why comparing prices before you fill is worth the few seconds it takes.

Rx.com checks current cash prices across more than 60,000 pharmacies and shows you a free coupon you can use at the counter, with or without insurance. Prices change often and are shown live on this page, so enter your ZIP above to see today's price near you. There is no manufacturer savings card for this generic; the coupon is simply a discounted cash price.

Paroxetine mesylate vs. other paroxetine forms and SSRIs

Paroxetine comes in more than one salt form. The mesylate salt (Pexeva, Brisdelle) and the hydrochloride salt (Paxil, generic paroxetine) deliver the same active paroxetine, though brand indications and dosing can differ. If you were prescribed a specific brand, compare it against the plain generic to see which costs less.

Paroxetine is one of several SSRIs. If you and your prescriber are weighing options, other commonly prescribed SSRIs include sertraline, escitalopram, and fluoxetine. You can also look up the specific brands Pexeva and Brisdelle. Never switch medications on your own; only your provider should change your treatment.

Important safety information

Paroxetine carries a boxed warning for an increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults under 25, especially during the first months of treatment or after a dose change. Watch for new or worsening mood changes and stay in close contact with your prescriber. Do not take paroxetine with, or within 14 days of, an MAO inhibitor because of the risk of serotonin syndrome.

Other risks include serotonin syndrome, abnormal bleeding (especially when taken with NSAIDs, aspirin, or blood thinners), low sodium (hyponatremia), and discontinuation syndrome if the drug is stopped suddenly, so any change should be tapered under medical guidance. Paroxetine is associated with an increased risk of heart-related birth defects, and Brisdelle is contraindicated in pregnancy. It may also impair judgment or motor skills. This is a summary, not medical advice; talk with your doctor or pharmacist about your full health history and all medicines you take.