Tradjenta
Tradjenta
What is Tradjenta?
Tradjenta (linagliptin) is a prescription medication used to improve blood sugar control in adults with type 2 diabetes. As a DPP-4 inhibitor, it helps the body increase insulin production after meals while reducing glucose production, making it an effective option when combined with diet and exercise.
Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe joint pain
- Shaking, trembling, sweating, fast or pounding heartbeat, faintness, hunger, confusion
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have gallstones, or a history of heart failure, alcohol abuse, or pancreas problems.
- This medicine may cause the following problems:Pancreatitis (swelling of the pancreas)Severe and disabling joint painHeart failureLow blood sugar levels
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness
Prescription savings · · · ·
What is Tradjenta ?
Tradjenta (linagliptin) is a prescription medication used to improve blood sugar control in adults with type 2 diabetes. As a DPP-4 inhibitor, it helps the body increase insulin production after meals while reducing glucose production, making it an effective option when combined with diet and exercise.
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe joint pain
- Shaking, trembling, sweating, fast or pounding heartbeat, faintness, hunger, confusion
- Blistering, peeling, red skin rash
- Large, hard skin blisters
- Trouble breathing, cold sweat, bluish-colored skin
- Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness
- Swelling in your hands, ankles, or feet
- Tell your doctor if you are pregnant or breastfeeding, or if you have gallstones, or a history of heart failure, alcohol abuse, or pancreas problems.
- This medicine may cause the following problems:Pancreatitis (swelling of the pancreas)Severe and disabling joint painHeart failureLow blood sugar levels
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness
Tradjenta Coupons & Prices
Tradjenta
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a Tradjenta coupon? Tradjenta (linagliptin) is a brand-name, once-daily tablet FDA-approved to help improve blood sugar control in adults with type 2 diabetes, used alongside diet and exercise. There is no generic version yet, so it can be costly at the pharmacy. Enter your ZIP above to see today's Rx.com cash price at pharmacies near you, and compare it against the manufacturer's savings card to find your lowest out-of-pocket cost.
What is Tradjenta and how does it work?
Tradjenta is the brand name for linagliptin, a medicine in the DPP-4 inhibitor class. It is FDA-approved as an add-on to diet and exercise to improve glycemic (blood sugar) control in adults with type 2 diabetes mellitus. It is not used for type 1 diabetes or for diabetic ketoacidosis. DPP-4 inhibitors like linagliptin help your body release more insulin after meals and lower the amount of sugar your liver makes, which helps keep blood sugar in a healthier range.
Tradjenta is often prescribed together with other diabetes drugs such as metformin. Linagliptin is also the active ingredient in two fixed-dose combination products: Jentadueto (linagliptin with metformin) and Glyxambi (linagliptin with empagliflozin). This is general information, not medical advice; your provider decides which option fits your treatment plan.
Tradjenta cost: manufacturer savings card vs. Rx.com cash coupon
The Tradjenta savings search results are usually split between the manufacturer's savings card and cash-price coupons. The manufacturer, Boehringer Ingelheim, offers an official Tradjenta savings and support program. Manufacturer copay cards like this are generally limited to people with commercial (private) insurance and typically exclude those with Medicare, Medicaid, or other government coverage. Terms, eligibility, and any dollar limits are set by the manufacturer and change over time, so check the official page for current details.
An Rx.com cash coupon works differently. It is not insurance and is not tied to your insurance, so it can help when you are uninsured, when you have Medicare or another plan the manufacturer card excludes, or when the manufacturer card is declined at the pharmacy. Because Tradjenta has no generic, prices can vary a lot from one pharmacy to the next. Enter your ZIP above to see today's price and compare pharmacies before you fill.
Tradjenta alternatives and related diabetes drugs
Tradjenta is one of several options for type 2 diabetes, and your provider may consider alternatives based on your health, other medicines, and cost. Related medicines people compare include:
- Linagliptin — the active ingredient in Tradjenta.
- Januvia (sitagliptin) — another DPP-4 inhibitor in the same class.
- Jardiance (empagliflozin) — an SGLT2 inhibitor.
- Trulicity (dulaglutide) — a once-weekly GLP-1 injection.
- Jentadueto and Glyxambi — fixed-dose combinations that contain linagliptin.
These medicines are not interchangeable and each has its own uses and precautions. Do not switch or add a medication on your own; talk with your provider or pharmacist about which is right for you.
Tradjenta safety and side effects
Tradjenta does not carry a boxed warning. A common side effect reported is nasopharyngitis (cold-like symptoms). More serious risks that have been reported include acute pancreatitis (which may be severe and, in rare cases, fatal) — stop the medicine and contact your provider if pancreatitis is suspected. Because it lowers blood sugar, there is a risk of hypoglycemia, especially when Tradjenta is taken with insulin or a sulfonylurea; your provider may lower the dose of those medicines.
Other reported reactions include serious hypersensitivity reactions such as anaphylaxis, angioedema, and exfoliative skin conditions; severe, disabling joint pain (arthralgia) seen with DPP-4 inhibitors; and bullous pemphigoid, a blistering skin condition that may require hospitalization — discontinue if it occurs. There have also been post-marketing reports of heart failure with DPP-4 inhibitors. This is not a complete list and is not medical advice. Read the manufacturer's information and talk with your provider about your personal risks and any side effects you notice.
This Tradjenta information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Tradjenta on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.