Hydroxychloroquine Sulfate
Hydroxychloroquine Sulfate 200MG
What is Hydroxychloroquine Sulfate?
Plaquenil is used to treat and prevent malaria. The generic version is Hydroxychloroquine. The average Plaquenil cash price is about $654 for a supply of 60 tablets, 200 mg. You can significantly lower your Plaquenil cost by using our free Plaquenil coupon card at participating pharmacies near you.Side Effects
- Muscle pain, tenderness, or weakness
- Unusual changes in mood or behavior, or thoughts of hurting yourself or others
- Lightheadedness, dizziness, fainting
Warnings
- This medicine may cause the following problems:Changes in vision, eye damageHeart problemsChanges in heart rhythm, including QT prolongationMuscle and nerve problemChanges in mood or behaviorLow blood sugar levelsSerious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart rhythm problems, diabetes, stomach or bowel problems, nerve problems, blood disorders (including G6PD deficiency, porphyria), psoriasis, or vision or eye problems. Tell your doctor if you drink alcohol.
Prescription savings · · · ·
What is Hydroxychloroquine Sulfate ?
Plaquenil is used to treat and prevent malaria. The generic version is Hydroxychloroquine. The average Plaquenil cash price is about $654 for a supply of 60 tablets, 200 mg. You can significantly lower your Plaquenil cost by using our free Plaquenil coupon card at participating pharmacies near you.- Muscle pain, tenderness, or weakness
- Unusual changes in mood or behavior, or thoughts of hurting yourself or others
- Lightheadedness, dizziness, fainting
- Increased hunger, headache, confusion, shaking, trembling, sweating
- Unusual bleeding or bruising
- Fast, pounding, or uneven heartbeat
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Blistering, peeling, red skin rash
- Blurred vision, hearing problems
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- This medicine may cause the following problems:Changes in vision, eye damageHeart problemsChanges in heart rhythm, including QT prolongationMuscle and nerve problemChanges in mood or behaviorLow blood sugar levelsSerious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart rhythm problems, diabetes, stomach or bowel problems, nerve problems, blood disorders (including G6PD deficiency, porphyria), psoriasis, or vision or eye problems. Tell your doctor if you drink alcohol.
Hydroxychloroquine Sulfate Coupons & Prices
Hydroxychloroquine Sulfate 200MG
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Looking for a hydroxychloroquine sulfate coupon? Hydroxychloroquine sulfate is the low-cost generic version of Plaquenil, an antimalarial and disease-modifying antirheumatic drug (DMARD) used to treat malaria, lupus, and rheumatoid arthritis. Even as an affordable generic, the cash price can vary widely from one pharmacy to the next, so comparing pharmacies matters. Enter your ZIP above to see today's hydroxychloroquine sulfate price at pharmacies near you. Rx.com compares prices across more than 60,000 pharmacies so you can find a lower cash price on your prescription.
What is hydroxychloroquine sulfate and how does it work?
Hydroxychloroquine sulfate is a 4-aminoquinoline medicine that belongs to two overlapping drug classes: antimalarials and disease-modifying antirheumatic drugs (DMARDs). It is sold under the brand name Plaquenil, and it is FDA-approved to treat uncomplicated malaria caused by susceptible strains of P. falciparum, P. malariae, P. ovale, and P. vivax, and to help prevent malaria in areas where chloroquine resistance has not been reported.
Beyond malaria, hydroxychloroquine is FDA-approved to treat chronic discoid and systemic lupus erythematosus (SLE) in adults, as well as acute and chronic rheumatoid arthritis in adults. It works differently from ordinary pain relievers, calming the overactive immune and inflammatory activity that drives autoimmune conditions rather than simply masking symptoms. Your provider decides whether it is appropriate for you.
How much does hydroxychloroquine sulfate cost without insurance?
Hydroxychloroquine sulfate is available as a generic, which usually makes it far more affordable than the brand-name Plaquenil. Even so, the cash price is not the same everywhere. Pharmacies set their own prices, and what you would pay can differ substantially between two stores in the same neighborhood, which is exactly why comparing before you fill is worthwhile.
Because prices change and are shown live, we do not list a fixed dollar figure here. Enter your ZIP above to see today's hydroxychloroquine sulfate price at pharmacies near you. Rx.com compares cash prices across more than 60,000 pharmacies, so you can bring a coupon for a lower price to the counter, with or without insurance. There is no manufacturer savings card for this generic.
Alternatives and related medications
Hydroxychloroquine is often one of several options a provider may consider for autoimmune conditions like lupus and rheumatoid arthritis. Depending on your diagnosis and response to treatment, your provider might discuss other DMARDs or related medicines. Only your provider can decide what is right for you.
- Plaquenil — the brand-name version of hydroxychloroquine sulfate
- methotrexate — a commonly used DMARD
- sulfasalazine — another DMARD option
- leflunomide — a DMARD used for rheumatoid arthritis
- chloroquine — a related 4-aminoquinoline antimalarial
Important safety information
This is a summary, not medical advice. Always talk with your provider or pharmacist before starting or changing hydroxychloroquine, and make sure they are fully familiar with the drug before it is used. A key concern with long-term or high-dose use is irreversible retinal damage (retinopathy), so baseline and periodic eye exams are required. Serious, life-threatening and even fatal heart problems have been reported, including cardiomyopathy and QT prolongation with dangerous rhythm disturbances (Torsades de Pointes); use caution alongside other drugs that prolong the QT interval.
Other serious risks include severe low blood sugar (hypoglycemia), blood cell and bone marrow problems, muscle or nerve damage, and severe skin reactions. Suicidal behavior has been reported. Hydroxychloroquine is not recommended for chronic (long-term) use in children, and extra caution is needed in people with G6PD deficiency, liver or kidney problems, psoriasis, or porphyria, which it may worsen. Report any vision changes, muscle weakness, mood changes, or unusual symptoms to your provider promptly.
This Hydroxychloroquine Sulfate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Hydroxychloroquine Sulfate on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.